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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAL1 All Species: 16.67
Human Site: S146 Identified Species: 33.33
UniProt: P17542 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17542 NP_003180.1 331 34271 S146 S L S Q P L A S L G S G F F G
Chimpanzee Pan troglodytes XP_001163354 331 34278 S146 S L S Q P L A S L G S G F F G
Rhesus Macaque Macaca mulatta XP_001088653 148 14676
Dog Lupus familis XP_852903 327 33732 A142 S L G Q P G G A C G F G F F G
Cat Felis silvestris
Mouse Mus musculus P22091 329 34260 S146 S L S Q P L A S L G S G F F G
Rat Rattus norvegicus Q66HH3 278 29939 P124 A G P F S I F P N S R L K R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518368 179 19831 V25 M F S N N N R V K R R P S P Y
Chicken Gallus gallus P24899 311 33749 T139 N L G Q P L G T I G S G F F G
Frog Xenopus laevis O73823 394 43024 S221 G L N Q P L A S D N S G Y F G
Zebra Danio Brachydanio rerio O93507 324 35687 A144 S N M T T P L A T I N S G F A
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 A168 N L A Q P L A A I N S L G G E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792477 400 43713 Q188 Q Q Q P Q P H Q A P T N P H Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 41.9 92.7 N.A. 93 35.3 N.A. 41.6 56.1 49.4 50.7 38.5 N.A. N.A. N.A. 25.7
Protein Similarity: 100 99.6 42.2 93.6 N.A. 94.5 44.4 N.A. 45.3 62.8 56.8 61 50.9 N.A. N.A. N.A. 39.7
P-Site Identity: 100 100 0 60 N.A. 100 0 N.A. 6.6 66.6 66.6 13.3 40 N.A. N.A. N.A. 0
P-Site Similarity: 100 100 0 66.6 N.A. 100 13.3 N.A. 6.6 86.6 80 26.6 66.6 N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 42 25 9 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 9 0 9 0 0 9 0 0 0 9 0 42 59 0 % F
% Gly: 9 9 17 0 0 9 17 0 0 42 0 50 17 9 50 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 9 0 0 17 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % K
% Leu: 0 59 0 0 0 50 9 0 25 0 0 17 0 0 0 % L
% Met: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 9 9 9 9 9 0 0 9 17 9 9 0 0 0 % N
% Pro: 0 0 9 9 59 17 0 9 0 9 0 9 9 9 0 % P
% Gln: 9 9 9 59 9 0 0 9 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 9 0 0 9 17 0 0 9 9 % R
% Ser: 42 0 34 0 9 0 0 34 0 9 50 9 9 0 0 % S
% Thr: 0 0 0 9 9 0 0 9 9 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _